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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '724e6f87f6ed14446271ea3df114faaed5de937aa2f9aa526bd6472a8aea09b9' 
  AND token = 'mDUe2rGYHw4n+AWk7rCZXeGQ38Tg2Xrf87W1GytdhPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}