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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c44e2b1053e02284cff2bba3026174e9ab550c98ab9ae225896d6dba156b2c4' 
  AND token = 'we1cO47tnsAw22oZPcKX17aoKERAzt3zZdSnB9wesNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}