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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be19aaa4b0abf6b402e4c138bf9ca6b29fb933e275e540a365a665862b3a8414' 
  AND token = 'AT+dj352zJydmeOkhqsoxd/UqrJd+yA4qwBbLixkYqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}