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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de249a7ed1c5001ce709ebb21458e8481d2f39ea1646a548ce89095fdf0398b2' 
  AND token = '+pZ4L0oBOxqtF6Bd4UXMoHFQBJVAi29LLGG3QP6j6gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}