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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a385f28795fa03efd140f61b4d8806b38dc2f1b760393c0a165ce9be83043d1' 
  AND token = '3wMkUheQoL5Iu5NH+dTwdrYA7CJh1lr3mgdoBRUD3AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}