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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4029df77ba9e158ef446324c820cb21b77368da5099e3dedb37731553bd15be9' 
  AND token = 'a38tthLnPDs+wp4Jb5tP0tAicB9xs0cDrnkRQgFgJVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}