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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '383ab343156ec9bf235e2f0e8eaa3d7ace978440eba8c3caa342949c235198f3' 
  AND token = '0t8q0v+yFg9UztqGCsxqZhB7mQSgFBolfbVjMu4Y4RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}