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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20d2d37f14449108f145374b1cdd242d616a03e2fe217bdc7af0369e29a9fb2b' 
  AND token = 'sAMg32XVPGJHho3dzVmILvTdPvQwSS9yB1L4Tlr5oQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}