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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f8307dc7d1fecf8e59e3bd05764c6fbf89bcd0fdfeaae98ef20b498f4377b9' 
  AND token = 'Mxwsf4Kt5G1cNc2J6DinAZ9KbSNlgoJEz9o2nj161m4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}