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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c107c6a281d496e61c11cf56ebf21d6d789f19e6fe5fe1b5076cf55da362d151' 
  AND token = '0/JxMbq7JHzOLdOjo3zCJeC+kWlWNJjVKHhfPiW8USU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}