SELECT 
  pfv.feature_id, 
  pfv.product_id, 
  pfv.variant_id, 
  fv.position, 
  fvd.variant 
FROM 
  cscart_product_features_values AS pfv 
  INNER JOIN cscart_product_feature_variants AS fv ON pfv.feature_id = fv.feature_id 
  AND pfv.variant_id = fv.variant_id 
  INNER JOIN cscart_product_feature_variant_descriptions AS fvd ON pfv.variant_id = fvd.variant_id 
  AND fvd.lang_code = 'ru' 
WHERE 
  pfv.feature_id IN (193, 3) 
  AND pfv.product_id IN (
    53, 22713, 21, 22714, 22712, 46, 22715, 
    22716, 51496, 21567, 91, 50989, 105, 
    48, 49, 92
  ) 
  AND pfv.lang_code = 'ru'

Query time 0.00222

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "20.10"
    },
    "nested_loop": [
      {
        "table": {
          "table_name": "pfv",
          "access_type": "range",
          "possible_keys": [
            "PRIMARY",
            "fl",
            "variant_id",
            "lang_code",
            "product_id",
            "fpl",
            "idx_product_feature_variant_id"
          ],
          "key": "idx_product_feature_variant_id",
          "used_key_parts": [
            "product_id",
            "feature_id",
            "lang_code"
          ],
          "key_length": "12",
          "rows_examined_per_scan": 34,
          "rows_produced_per_join": 34,
          "filtered": "100.00",
          "using_index": true,
          "cost_info": {
            "read_cost": "3.99",
            "eval_cost": "3.40",
            "prefix_cost": "7.39",
            "data_read_per_join": "26K"
          },
          "used_columns": [
            "feature_id",
            "product_id",
            "variant_id",
            "lang_code"
          ],
          "attached_condition": "((`test_uchur_k`.`pfv`.`feature_id` in (193,3)) and (`test_uchur_k`.`pfv`.`product_id` in (53,22713,21,22714,22712,46,22715,22716,51496,21567,91,50989,105,48,49,92)) and (`test_uchur_k`.`pfv`.`lang_code` = 'ru'))"
        }
      },
      {
        "table": {
          "table_name": "fv",
          "access_type": "eq_ref",
          "possible_keys": [
            "PRIMARY",
            "feature_id"
          ],
          "key": "PRIMARY",
          "used_key_parts": [
            "variant_id"
          ],
          "key_length": "3",
          "ref": [
            "test_uchur_k.pfv.variant_id"
          ],
          "rows_examined_per_scan": 1,
          "rows_produced_per_join": 2,
          "filtered": "6.81",
          "cost_info": {
            "read_cost": "8.50",
            "eval_cost": "0.23",
            "prefix_cost": "19.29",
            "data_read_per_join": "3K"
          },
          "used_columns": [
            "variant_id",
            "feature_id",
            "position"
          ],
          "attached_condition": "(`test_uchur_k`.`fv`.`feature_id` = `test_uchur_k`.`pfv`.`feature_id`)"
        }
      },
      {
        "table": {
          "table_name": "fvd",
          "access_type": "eq_ref",
          "possible_keys": [
            "PRIMARY"
          ],
          "key": "PRIMARY",
          "used_key_parts": [
            "variant_id",
            "lang_code"
          ],
          "key_length": "9",
          "ref": [
            "test_uchur_k.pfv.variant_id",
            "const"
          ],
          "rows_examined_per_scan": 1,
          "rows_produced_per_join": 2,
          "filtered": "100.00",
          "cost_info": {
            "read_cost": "0.58",
            "eval_cost": "0.23",
            "prefix_cost": "20.10",
            "data_read_per_join": "7K"
          },
          "used_columns": [
            "variant_id",
            "variant",
            "lang_code"
          ]
        }
      }
    ]
  }
}

Result

feature_id product_id variant_id position variant
3 21 7 0 XL
193 21 1357 0 S
3 46 26 0 размер XL
193 46 1358 0 M
3 48 8 0 S
193 48 1357 0 S
3 49 11 0 L
193 49 1358 0 M
3 53 8 0 S
193 53 1357 0 S
3 91 18 0 36x30
193 91 1365 0 32x30
3 92 10 0 M
193 92 1357 0 S
3 105 6 0 OSFA
193 105 1373 0 OSFA
3 21567 6 0 OSFA
3 22712 26 0 размер XL
193 22712 1357 0 S
3 22713 26 0 размер XL
193 22713 1357 0 S
3 22714 26 0 размер XL
193 22714 1357 0 S
3 22715 26 0 размер XL
193 22715 1357 0 S
3 22716 26 0 размер XL
193 22716 1357 0 S
193 50989 1373 0 OSFA
193 51496 1373 0 OSFA