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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21553ac29eb045370f918e859b02a93ee61d99f18248a84ef3a22ed7177f5dc9' 
  AND token = '/gPmZ2zKlibwCLzJr/0HbJ/baScUjdzNL6Mn4xIMl4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}