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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac0607d4dabf18645b7f4d5c7b0e858c658fb7f4f64b5e8015b3ada51e3fc94' 
  AND token = 'qNvRjAvzTRg51Eazd0MzaeAwBqy94J0xQhdg0Lkf1qI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}