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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35e1eceeb709040cd9680d02627d3e1dffcb2f9179f9795ba8ccfe0fc3fb2d85' 
  AND token = 'IIb5R1MVRkGxxlg2Kl13FTMcrc6GkbU3OKm92Xl7ank=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}