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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d30339cea96ce8631c1d62f47a6b83f44e4fdffdffab24303b0cc4795adbd1' 
  AND token = 'SLxR4sFQ6LcZo+dKYvaeDVFvmsVHy00uWoyJHT29Vo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}