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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c3b14920943f597c2365dc8f31936d1d25ef6c028c8a530abbed5d2abf0e5d' 
  AND token = 'mynxHllsbvV28S+rdHhEzzxC/S3kQ9UNyrFwoN3ybzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}