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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '358ad03c919cc2f5fcddfc024e2a8198e87fd6807d85f31b09101fe494e4b4ad' 
  AND token = 'E2yRmEX8h74qA5gQfe+pQdsISHNdjOf2uhkHeuaPdGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}