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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f55219c366a7d7e43562d2c3b0880e47e62563bce005930e7aeee3f3af82674c' 
  AND token = 'EIbYflyD6BPZ9PVHo01QDp7MD90RHiMfCHUm/e4fyGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}