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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5a3a18c5afd3b8541296498cf9571a2112305ca27705e735cae636c55579090' 
  AND token = 'hxHwSlo5IJM/JHRCdDuTd6V6NJDxWsAcF5LIByBCdJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}