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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3934d140c7309c4649142b155e8dd99f4dae64e6cbd2a336203d44caef9ec345' 
  AND token = 'lJRygEcfHC+IH2lAf9oFrJeVVlT44jZIQRdbFdEXl8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}