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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d757e77d965659f98804987fd2b19d3d601a7f57a2e43d5f35549dce8764345' 
  AND token = 'cP/fVyeK6GBCmlXlpMj71CyZQSTsEgp5t6lRYRQY1qQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}