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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab9340ebfc2136dc85789433bd2974e0e4127bcb32b7d626fef05948f39b47d' 
  AND token = '2eDyjMU2+Zs1xML/LpSlN6W6OkqG+UheEWSHeJ6YeK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}