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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2783ea653bb53f94fd2ad557d7cde5e6e39d0210a1632c657bd3475c56335460' 
  AND token = 'NIk/lqRuoe6PBoqZystK/icqP7pp2pVvJ3uT85P/2BU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}