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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2888fae63e7918bdf7ba98b1efbe9f628bcbf92d63c0e4354fedf69746aca638' 
  AND token = 'r3q4e1Q7PxY9thMO9WIJe/Zcr8dH9d5BvsH098N0xDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}