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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bb12dfdd5629afa839bba24a325eaf80bfea3e177ebd68b15eb28d6ed6812a' 
  AND token = 'nsLEngSmm3LgEfwocvty94xn/u+nU4YpbJhL0GhFZVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}