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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c6041063ec2f38827ad6efaf2274a3e9f012d2f6d778fd9ae6822d366d02872' 
  AND token = 'UpMc74rM1k3P6FGa4MjO+mYhikJgYhSsV/klVVnNLVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}