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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a781891379f026732cba8b40825e3b0a85b98c7989ae54d6e93f9e5f46d0810' 
  AND token = 'kX8vtPBXtPciEoydm2u8TiVYn9lRm2e0IqcxPnZzstw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}