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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648274eb6eae0f3b32c05f20452c5e4097bb4e71fc38a90eed184997ef85f2b1' 
  AND token = 'xLvMhWRWzvr2W+KDmQRuA9VrNIeS1Hl8wa0Qx+Bw4Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}