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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39352c8ca19ef4ebfc38b752a165583230ec6c4f80bf123f2372480e503032df' 
  AND token = 'O/ZSk/Af8x9uWrfQashy9tUzmHc7wgRx4/bVd9EfFUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}