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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '872a3a8cff5f3a39e08d827b6e2d9e50db6055bf1b25e7862fa651e1233edea2' 
  AND token = 'NOovDy6CkxqzGmnS5RHZF8x1UuWxDFLgPSvhrj/0/+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}