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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c04981bc4551ecb8ba2ff148ab17b3b4492db883546dd3aa3c36bb572c006b' 
  AND token = 'gtHtrolIVrdVbzvAtXQK/5GsyUb6L1CUtK+6gWnxdHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}