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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b8a38b04a5e385d2be756bdfec0296ac48aa053cbdf636eee426a5481b06b6c' 
  AND token = 'VY0ijguOhluZ578I+uR0qVErBzA27Spidu97VXjph3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}