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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e23b3cb43d4b5c9d4fe20bbe3eff2d3d87a54acda23adc7d967b21b47aa2670' 
  AND token = '8/epfkWJwbg9SWZXDYRu4acfXFObykODk1zA6SP5qC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}