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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6457dfdacaa775f9d6b778548282dfeeed23b93dcad2481012387c6d7397fed' 
  AND token = 'kx2G+Q08Bw0AjN2mzA/BY8hINSLZJ0f+A+STBNP2Dpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}