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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27ced5eb42041e516eb957b9f3b1058a8f7bd690316a6115b92d1ca4b4af723f' 
  AND token = 'Ax5bGR1JlHGhFFCkgVp9PmMIdpnIwI5xTHjmpE+drMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}