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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8a4307b2c2483436d674641aa1ae214a198ca79f4217f05f0bd81a97f453cd4' 
  AND token = 'xyUc4USyLCLTcxyYB1R0A6wTUnXqVwwhHhiuK1mIiyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}