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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb0a92f48651c79a8a9a4c72c5295829f0173f1fe2d017f35277c8e996cf7823' 
  AND token = 'HC3e+SJWHgJ5yrMw7IVWCWEl3OBfZB4GHknGNVS3uC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}