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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7f39541a0b27fc3cb2dc0171cec31c06645403a5717f5359a13e56af3ed5d5' 
  AND token = 'TmH9+cVGpSNTwF6U1TqtFgkj2JpKXaQ5quPTYvcdfKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}