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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e7ee4063aa1f3056da7d7bb5332f386fe04fa3fb607251a5d612ac25559a70e' 
  AND token = 'k22E0/GP0tQgT63mAk5XX3w2PiYvPKI+Aqn80PlVzLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}