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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6f97d00c9d3c7645faec9b2bf26192be380efaa3f2de1ac8e715da90a72f90c' 
  AND token = 'Jk/fv07sz6UZGYJXexB+s70kJS3a+Ze3U4B3zXtxyBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}