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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46eae6f42d06e800ab6990dfc9cc5886040fc244efb97802a4d2b4cc59fb64a8' 
  AND token = '0CPpJ7/PwsDwlEANkF5/XbQ9G2LEEkq13D+5W0ZwJHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}