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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20db6fa9a1b61a2447857b36fae84c31a7c0870dcf28f4873330543509af60e3' 
  AND token = 'CABe4v8gcObO/YwvTXrsh2f/9VgcRdqaOODZEcx+4Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}