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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a37f6c178c4d9f1dd514f6db1e4731105a5a03098e5ab70500f1c2f9eb1eefe7' 
  AND token = 'TqXgMANg+2dgijuFMR5Te6tMe021rRzOVtT5hI0Ixwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}