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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c8a453fa6d033fc6a9eebc264e1675c7f5e7f16d4401b7efbf24799bb9b5542' 
  AND token = 'oZYZ38k051uh3xHaU7NDNgfR24oeMIRSkD/yY5FFToQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}