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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4366e3c6ea8c2dd1d95dd51ce222a34172781d88ab48c2635f1ec4d59e3acf46' 
  AND token = 'sGU6KMYKdXax0+PuSRnn0V/EM79e4r4Wilh4o0XtV0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}