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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f259c1d31efbacc6ce67a35223a014cc4df5352bdb7e30c400e5345e0dc7bb9' 
  AND token = 'KsxCUIIWyXx1fYIMLrLDR6QgH1/+Qw+XHvuxWje6P3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}