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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ed8cabfe09d9e3f006c9134342be4dff81b364281aeaa4fbb7ddd2d199a1020' 
  AND token = '87kf1YQoI1K4E4MMoCHwe82CZG7zbe0CRZuNyjlWDks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}