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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecdb8fa755491d331d47b4732c151e0786c02a99c1a77436691fed697df37e9c' 
  AND token = 'OvTFI2ZtdLE1N1mvsaztZPkqy35XqSophqu4TE0vxrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}