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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0c0c76ffeb37e9f3ae4a8274e1f634b37a2677e0803009c085f6a086041a50' 
  AND token = 'fIOfx274pWdIzossH+t+EV3JL1owfSzP/jn2dnELMd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}