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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef23acf9fb8fc6bd801e29c95a02a05996022a1726ce48b4b19df4a5a8371407' 
  AND token = 'fiq49javFQE57ACXqOfOHtx3/ZtIjypJbmhMC8QbOUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}